A new drug target for chemically induced Parkinson's disease

More than three decades ago, scientists discovered that a chemical found in a synthetic opioid, MPTP, induced the onset of a form of Parkinson's disease. In a new study led by scientists from the School of Veterinary Medicine, researchers found that an enzyme in the body can metabolize compounds formed in the brain from alkaloids present in certain foods and tobacco into MPTP-like chemicals, triggering a neurodegenerative condition in mice.

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Artificial intelligence learns to recognize nerve cells by their appearance

Is it possible to understand the brain? Science is still far from answering this question. However, since researchers have started training artificial intelligence on neurobiological analyses, it seems at least possible to reconstruct the cellular structure of a brain. New artificial neural networks developed by the Max Planck Institute of Neurobiology and Google AI can now even recognize and classify nerve cells independently based on their appearance.

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Cytotoxicity and physical properties of glass ionomer cement containing flavonoids

At the 97th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 48th Annual Meeting of the American Association for Dental Research (AADR) and the 43rd Annual Meeting of the Canadian Association for Dental Research (CADR), Aline de Castilho, University of Campinas, Brazil, presented a poster on "Cytotoxicity and Physical Properties of Glass Ionomer Cement Containing Flavonoids." The IADR/AADR/CADR General Session & Exhibition is held at the Vancouver Convention Centre West Building in Vancouver, BC, Canada from June 19-22, 2019.

* This article was originally published here

Moral lessons in children's television programs may require extra explanation

Children's television programming often contains moral lessons and examples of inclusiveness, but children may struggle to comprehend and transfer the situations presented on an animated production to their own lives, University of California, Davis, research suggests.

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Bacteria live on our eyeballs—and understanding their role could help treat common eye diseases

You may be familiar with the idea that your gut and skin are home to a collection of microbes—fungi, bacteria and viruses—that are vital for keeping you healthy. But did you know that your eyes also host a unique menagerie of microbes? Together, they're called the eye microbiome. When these microbes are out of balance—too many or too few of certain types—eye diseases may emerge.

* This article was originally published here

Ice lithography: Opportunities and challenges in 3-D nanofabrication

Nanotechnology and nanoscience are enabled by nanofabrication. Electron-beam lithography (EBL), which makes patterns down to a few nanometers, is one of the fundamental pillars of nanofabrication. In the past decade, significant progress has been made in electron-beam-based nanofabrication, such as the emerging ice lithography (IL) technology, in which ice thin-films are used as resists and patterned by a focused electron-beam. The entire process of IL nanofabrication is sustainable and streamlined because spin coating and chemical developing steps commonly required for EBL resists are made needless.

* This article was originally published here

Combination of drugs may combat deadly drug-resistant fungus

As health officials in New Jersey, Illinois and New York State scramble to contain the spread of a highly infectious and deadly fungus, microbiologists at Beth Israel Deaconess Medical Center (BIDMC) have shown that a combination of anti-fungal and anti-bacterial medications may be an effective weapon against the recently discovered multidrug resistant, Candida auris (C. auris).

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Reforming pharmacy benefit manager practices may lead to drug cost savings

Efforts to control health care costs in the United States often focus on the listed prescription drug prices, but a perspective published by the Journal of the American Medical Association suggests that unregulated pharmacy benefit manager practices also may contribute to escalating expenses.

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Autoimmunity and chair-side risk assessment of temporomandibular disorders

At the 97th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 48th Annual Meeting of the American Association for Dental Research (AADR) and the 43rd Annual Meeting of the Canadian Association for Dental Research (CADR), many oral and poster presentations centered around temporomandibular disorders, or TMD. The IADR/AADR/CADR General Session & Exhibition is held at the Vancouver Convention Centre West Building in Vancouver, BC, Canada from June 19-22, 2019.

* This article was originally published here

Engineers 3-D print flexible mesh for ankle and knee braces

Hearing aids, dental crowns, and limb prosthetics are some of the medical devices that can now be digitally designed and customized for individual patients, thanks to 3-D printing. However, these devices are typically designed to replace or support bones and other rigid parts of the body, and are often printed from solid, relatively inflexible material.

* This article was originally published here

Your brain activity can be used to measure how well you understand a concept

As students learn a new concept, measuring how well they grasp it has often depended on traditional paper and pencil tests. Dartmouth researchers have developed a machine learning algorithm, which can be used to measure how well a student understands a concept based on his or her brain activity patterns. The findings are published in Nature Communications.

* This article was originally published here